Test Description
The Kappa and Lambda Light Chains test measures the levels of two types of light chains—kappa and lambda—in the serum. These proteins are produced by plasma cells and are essential components of immunoglobulins (antibodies) that help the immune system combat infections. The test specifically assesses free light chains, which are light chains that are not attached to heavy chains, and calculates the kappa/lambda ratio to provide insights into various plasma cell disorders.
Indications of the Test
This test is primarily used to:
- Diagnose and monitor plasma cell disorders such as multiple myeloma and primary amyloidosis.
- Evaluate symptoms like bone pain, anemia, kidney disease, and recurrent infections that may be linked to plasma cell disorders.
- Monitor treatment effectiveness in patients already diagnosed with these conditions.
Patient Preparation/Instructions
No specific preparation is required before the test. However, patients should inform their healthcare provider of any medications they are taking, as some may need to be paused prior to testing.
Typical Reference Values
Normal reference ranges for serum free light chains are approximately:
- Kappa Light Chains: 3.3 – 19.4 mg/L
- Lambda Light Chains: 5.7 – 26.3 mg/L
- Kappa:Lambda Ratio: 0.26 – 1.65
These values can vary based on the testing method and laboratory standards.
Turnaround Time
The results of the Kappa and Lambda Light Chains test are typically available within two weeks.
Order This Test
To order the Kappa and Lambda Light Chains test, please click the ‘Order Test’ button and add it to your cart.